Journal of Psychiatric Insight Review

Open Access • Peer Reviewed • Quarterly Publication

Lamotrigine-Induced Rash and Facial Swelling in a 27-Year-Old Female: A Case Report

Authors: Harleen, Saloni, AK Seth1 and Col Navtej Singh
Published: 2025-11-30
Pages: 01-4
DOI: 10.63721/25JPIR0122
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Abstract

Lamotrigine, a widely used antiepileptic and mood stabilizer, is associated with a risk of dermatologic hy persensitivity reactions, which can range from mild rashes to severe cutaneous adverse reactions. We report the case of a 27-year-old female with recurrent depressive disorder who developed widespread rash and fa cial swelling following initiation of Lamonex SR (lamotrigine) 100 mg once daily without titration. Prompt recognition and discontinuation of the drug led to complete resolution of symptoms. This case highlights the importance of careful titration and early monitoring when initiating lamotrigine.

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© 2025 The Author(s). Published by WM Journals.

This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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