Journal of Clinical Oncology & Advanced Therapy

Abstract

Background Keloids are benign fibroproliferative dermal tumors that arise from dysregulated wound healing, with a high er prevalence in individuals with darker skin phototypes. They typically develop at sites of trauma including surgical wounds, acne, piercings, burns, or vaccination sites. Keloid formation in measles rash scars has not been previously described in the literature.

Case Presentation A 33-year-old African American female presented with multiple extensive keloids (the largest measuring ~10 cm) distributed across the posterior thorax, neck, anterior chest, breasts and upper extremities. The lesions emerged approximately six years prior, specifically localized to areas of previous scars from measles rash. Management involved a multidisciplinary approach; surgical resection with adjuvant radiotherapy was rec ommended due to the high risk of recurrence.

Conclusion This case identifies a novel association between measles-induced cutaneous inflammation and subsequent keloidogenesis. Understanding this potential trigger is essential for clinicians to optimize early intervention and management strategies.