Journal of Preventive Medicine & Infectious Diseases

Open Access • Peer Reviewed • Bi-Monthly Publication

Interconnection Between Pupil Dilation and Involuntary Semen Discharge: Role of Sympathetic Activation and Hormonal Modulation

Authors: Abhijeet Kulkarni1, Arjun Abhijeet Joshi1, Rahul Hajare1
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Abstract

Abstract

Pupil dilation (mydriasis) and involuntary semen discharge are distinct physiological events that share a common regulatory framework involving the autonomic nervous system and neuroendocrine signaling. Both responses are significantly influenced by sympathetic nervous system activation and modulation by key hormones and neurotransmitters. This review summarizes the mechanistic pathways linking these phenomena, emphasizing the role of catecholamines, androgens, and central neurotransmitters. Understanding this interconnection provides insight into normal physiological reflexes and helps differentiate them from pathological conditions.

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© 2026 The Author(s). Published by WM Journals.

This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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