Journal of Advanced Diabetes Research

Abstract

The investigation of fenugreek seed extract transdermal patches for the treatment of diabetes mellitus is reported in this paper. Trigonella foenumgraecum, a member of the Leguminosae family, is the source of fenugreek seed extract. used to decrease blood cholesterol, treat diabetic mellitus, and other conditions. It contains active ingredients such as trigonelline, choline, and others that contribute to the antidiabetic effects. The extract's galactomannans content is what hydrates the skin. As a result, a topical fenugreek extract formulation may improve penetration and be primarily absorbed at a particular skin absorption site. Fenugreek extract-containing transdermal patches were created and assessed according to a number of criteria. After six hours, the drug content shows over 90% drug release. The 2:2 ratio was determined to have the maximum release among the various formulations. The findings show that a transdermal drug delivery system's regulated release can also increase therapeutic efficacy, patient compliance, and prevent adverse effects that come with traditional medications.