Journal of Innovative Clinical Trials and Case Reports

Open Access • Peer Reviewed • Bi-Monthly

Review on Artificial Intelligence in Clinical Trial Design and Optimization: Current Trends and Future Directions

Authors: Ch Bijayalaxmi, Thota Rajitha and Satish Kumar Vemavarapu
Published: 2025-09-18
Pages: 1-8
DOI: 10.63721/25JCTC0117
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Abstract

Clinical trials are crucial for advancements in medicine, but they are frequently costly, time-consuming, and prone to failure. Artificial Intelligence (AI) is becoming a game-changing technology that might completely change how clinical trials are designed and optimized. AI can improve patient recruitment, optimize trial pro tocols, enable adaptive designs, predict outcomes, and more effectively integrate real-world data by utilizing machine learning (ML) algorithms, natural language processing (NLP), and predictive analytics. This review explores the present applications of AI in clinical trial streamlining, discusses the challenges and ethical con siderations, and examines future directions, such as the potential of in silico trials and digital twins.

Copyright & License

© 2025 The Author(s). Published by WM Journals.

This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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