Journal of Biomedical Advancement Scientific Research

Abstract

Chemotherapy is a primary modality in cancer treatment but is commonly associated with various adverse effects that may lead to serious complications if not detected early. Conventional monitoring after chemotherapy often relies on scheduled visits and passive reporting, which can delay clinical intervention and increase the risk of complications and hospital readmission. This study aimed to evaluate the effectiveness of the Hermina CareTrack Remote Patient Monitoring (RPM) system, based on the Common Terminology Criteria for Adverse Events (CTCAE), in improving early detection of chemotherapy-related side effects, accelerating clinical response time, and reducing complication severity and readmission rates. A Quasi Experimental Study was conducted involving 50 chemotherapy patients at Hermina General Hospital Sukabumi. Participants were divided into an intervention group (RPM-based monitoring) and a control group (conventional care), each consisting of 25 patients. Patients in the intervention group reported daily symptoms through a web-based system integrated with CTCAE version 5.0, while healthcare providers monitored patient conditions via a dashboard. Outcomes measured included severity of side effects, response time, incidence of complications, and readmission rates. Statistical analysis was performed with a significance level of p < 0.05. The intervention group demonstrated a lower proportion of severe side effects (grade ≥3) compared to the control group (20% vs. 36%, p = 0.041). The average response time was significantly faster in the intervention group (38 ± 15 minutes) than in the control group (240 ± 45 minutes; p = 0.001). CTCAE based RPM using the Hermina CareTrack system improves early detection of chemotherapy side effects and accelerates clinical response, with potential to reduce complication severity and readmission rates.