Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated ste atohepatitis (MASH) are increasingly prevalent conditions that can lead to liver dysfunction, inflammation, and f ibrosis. While traditional treatments focus on lifestyle modification and pharmacologic interventions, osteo pathic manipulative treatment (OMT) offers a unique approach to improving physiological function through enhancing mobility and circulation. This literature review explores the potential role of OMT in improving thora coabdominal motion and its subsequent impact on liver health, specifically in patients with MASLD and MASH. OMT techniques such as diaphragmatic release, rib raising, and thoracic spine mobilization have been shown to enhance diaphragmatic function, venous return, and lymphatic drainage, all of which are crucial for maintaining optimal liver perfusion and reducing congestion. By improving thoracic and abdominal mo bility, OMT may indirectly benefit liver function by promoting better circulation, reducing fluid buildup, and decreasing systemic inflammation. Although limited studies exist directly linking OMT to liver health, this re view synthesizes existing research on OMT's effects on thoracoabdominal mobility and explores the theoret ical mechanisms through which these benefits could be extended to liver function in MASLD/MASH patients. Further research is needed to evaluate the clinical impact of OMT on liver disease outcomes. Still, the phys iological rationale provides a promising area for future investigation in osteopathic and liver health care.

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